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FARE INSIEME - Ep. 92 - Opocrin, the small research laboratory that has grown into a big one

«We listen to the needs of patients»

16/11/2022

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Thinking big also means researching and innovating in a big way: this is the story of the pharmaceutical company that was set up in Modena and that now boasts a turnover of €220 million with over four hundred employees. But, most of all, that provides concrete answers for global health. For FARE INSIEME, Giampaolo Colletti interviewed Federico Saetti, CEO of Opocrin

of Giampaolo Colletti
@gpcolletti

Photocredit: Giacomo Maestri e Francesca Aufiero

What if? This is an open question even visionary entrepreneurs at times do not know how to answer, although they are aware of how important it is. Federico Saetti is among them. Maybe he did not even imagine what heights he and the pharmaceutical company he leads would reach. Yet the projects and figures tell a success story in that land of innovation that also bets on pharmaceutical research.  Saetti has become the Chief executive officer of Opocrin after working for many years in the development and commercial teams. The company is located in the Modena area, and more precisely in the small town of Corlo di Formigine. The production facility is instead located in Nonantola. It is in this part of Emilia that this gem is located, which has become a pharmaceutical business capable of providing targeted answers to employees. What if? This is the question that was also asked by pharmacologist Pietro Banchini when he set up the small research laboratory from scratch, based on active biological principles and which would grow over the years. It was 1964 and the objective, just like today, was to look to nature for the pharmaceutical active principles suitable for humans, isolate them and make them available on the market using the best and safest technology. “This is the third generation as Opocrin was founded by my maternal grandfather Pietro Bianchini, a well-known pharmacologist esteemed by the international scientific community. My father took over in 2007 and handed things over to me in 2017, even though I had already started working for the company in 2007, when I was only 21, starting off with production and moving on to the commercial department. I can say I was born and bred within the company,” recalls Saetti.

Opocrin’s challenges.
Local roots and a global mission. Today, Opocrin is a global leader in the production of heparin derivatives. Its success is derived from its history. It currently boasts a commercial network enabling it to operate in over 50 countries. The objective: contribute to scientific progress to improve health. Opocrin works in close contact with selected partners to develop new innovative products thanks to the possibility of managing the project on a broad spectrum, from the supply of active principles for clinical studies, to the industrialisation of production for commercial purposes. The turnover is €220 million and the company employs 374 employees, with many new open positions. Over the past two years, it strengthened the part linked to acquisitions and became a group in 2020. “10% of our turnover currently derives from the pharmaceutical world, while 90% is linked to active principles. But the figures will switch over in the future,” stresses Saetti. The company produces life-saving products such as heparin. Over the past few years, it developed new by-products precisely from heparin, i.e. solutions with no anticoagulant and antithrombotic activity that have paved the way for new therapeutic areas. In this case too, research means hope. Today, the organisation makes it possible to follow the entire life cycle of a product, from the raw material to commercialization. “We specialize in the research and development of complex molecules with the objective of discovering new potential and new life-saving treatment approaches. We put research at the service of health and are always searching for new therapeutic approaches,” reports Saetti. Since its establishment, the company has been committed to contrasting glaucoma, the eye disease characterized by an abnormal increase of intraocular pressure responsible for damaging the optic nerve and therefore a possible cause of blindness. Opocrin has been focusing on contrasting the progression of the damage and has set up a study dedicated to the quality of life that has involved 220 patients in Italy, Spain, Belgium and Greece. “It is an invalidating disease to which our group has contributed to an extraordinary improvement in the quality of life of patients, with measurable scientific progress and indisputable clinical findings,” stresses Saetti.

Future in research.
Ambitions that grow. Opocrin has acquired Laboratori derivati organici, a company specializing in the production of active pharmaceutical principles, mainly heparin and heparinoids.    It has thus become one of the leading heparin producers in the world. But there is more to this: their research also focuses on studying the molecule that facilitates the onset of birth. The results of the study phase on tafoxiparin, i.e. modified heparin, were excellent. “This opens up a new era for the pharmacological induction of labour. About a quarter of pregnant women are subjected to labour induction by pharmacological and mechanical methods, which are not always effective. This is a way to make this incredible event in the life of a couple even safer for the mother and child,” concludes Saetti. Once again, Opocrin faces contemporary challenges with determination. The future stems from health and the awareness that science steers our lives.

https://podcast.confindustriaemilia.it/

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